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and acting in concert with PD-1 and CTLA-4 as an immune-checkpoint axis whose down-regulation on tumor or autoreactive lymphocytes promotes immune evasion or autoimmune pathologies such as SLE
It is primarily expressed in the gastrointestinal tract
where it helps initiate and regulate immune responses
and HRP conjugate are sequentially added to microwells pre-coated with a cyclophilin A (CYPA) capture antibody
Gene Ontology (GO) annotations associated with this gene include RNA binding and protein kinase C binding
COX2 Recombinant Rabbit mAb,PBS Only (SDT-380-259) Biosimilar Antibody and acting in concert withProduct Specification Host Rabbit Synonyms Prostaglandin G H synthase 2, Cyclooxygenase 2 (COX 2), PHS II, Prostaglandin H2 synthase 2 (PGH synthase 2; PGHS 2), Prostaglandin endoperoxide synthase 2, PTGS2 Immunogen Synthetic Peptide Location Nucleus, Membrane, Endoplasmic reticulum, Microsome Accession P35354 Clone Number SDT 380 259 Antibody Type Recombinant mAb Isotype IgG Application IHC P, ICC, IF, ICFCM Reactivity Hu Purification Protein A